a baumannii type strain atcc 19 606  (ATCC)

Journal: Emerging Microbes & Infections

Article Title: A novel CXCL8(3–72) K11R/G31P–BPI 233 hybrid protein modulates neutrophil-driven inflammation and protects against carbapenem-resistant Acinetobacter baumannii infection

doi: 10.1080/22221751.2026.2741787

Figure Lengend Snippet: Dose-dependent bactericidal activity of G31P–BPI 233 . (A) Heatmap summarizing the mean bactericidal rates against six reference strains and five clinical CRAB isolates. (B–E) Dose–response comparison of G31P–BPI 233 , a noncovalent G31P + BPI 233 mixture, BPI 233 alone, and G31P alone against clinical A. baumannii isolates 99391 (B), 99393 (C), and 99394 (D), and A. baumannii ATCC BAA-1605 (E). Component doses were molar-matched to the corresponding fusion-protein doses. Data are presented as mean ± SD.

Article Snippet: Below, four line graphs are labeled Clinical Acinetobacter baumannii 99391, Clinical Acinetobacter baumannii 99393, Clinical Acinetobacter baumannii 99394, and Acinetobacter baumannii ATCC BAA hyphen 1605.

Techniques: Activity Assay, Comparison

Journal: Emerging Microbes & Infections

Article Title: A novel CXCL8(3–72) K11R/G31P–BPI 233 hybrid protein modulates neutrophil-driven inflammation and protects against carbapenem-resistant Acinetobacter baumannii infection

doi: 10.1080/22221751.2026.2741787

Figure Lengend Snippet: G31P–BPI 233 protected mice against carbapenem-resistant Acinetobacter baumannii infection. (A) Survival of mice with lethal CRAB septicemia treated with saline (n = 15) or G31P–BPI 233 (n = 10). (B–G) Mice were intranasally challenged with A. baumannii ATCC BAA-1605 and treated with saline, G31P, BPI 233 , an equimolar G31P + BPI 233 mixture, G31P–BPI 233 , or colistin (n = 5 per group). Uninfected mice served as normal controls (n = 3). Samples were collected 24 h after infection. (B) Representative lung H&E staining; original magnification, 20×. (C) Lung injury scores. (D, E) IL-6 and TNF-α levels in bronchoalveolar lavage fluid. (F) Lung bacterial burden expressed as log10 CFU/g tissue. (G) Endotoxin activity in lung homogenates. Component doses were molar-matched to the corresponding fusion-protein dose. Data are presented as mean ± SEM. ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001.

Article Snippet: Below, four line graphs are labeled Clinical Acinetobacter baumannii 99391, Clinical Acinetobacter baumannii 99393, Clinical Acinetobacter baumannii 99394, and Acinetobacter baumannii ATCC BAA hyphen 1605.

Techniques: Infection, Saline, Staining, Tissue, Activity Assay

Journal: Emerging Microbes & Infections

Article Title: A novel CXCL8(3–72) K11R/G31P–BPI 233 hybrid protein modulates neutrophil-driven inflammation and protects against carbapenem-resistant Acinetobacter baumannii infection

doi: 10.1080/22221751.2026.2741787

Figure Lengend Snippet: G31P–BPI 233 limits neutrophil-associated inflammation during CRAB pneumonia. Mice were intranasally infected with A. baumannii ATCC BAA-1605 and treated with saline, G31P, BPI 233 , an equimolar G31P + BPI 233 mixture, G31P–BPI 233 , or colistin (n = 5 per group). Uninfected mice served as normal controls (n = 3). Samples were collected 24 h after infection. (A–D) Representative flow-cytometry plots and quantification of CD45⁺CD11b⁺Ly6G⁺ neutrophils among lung (A, B) and peripheral blood (C, D) leukocytes. (E, F) Pulmonary levels of MPO and extracellular dsDNA. Component doses were molar-matched to the corresponding fusion-protein dose. Data are presented as mean ± SEM. ns, not significant; * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001.

Article Snippet: Below, four line graphs are labeled Clinical Acinetobacter baumannii 99391, Clinical Acinetobacter baumannii 99393, Clinical Acinetobacter baumannii 99394, and Acinetobacter baumannii ATCC BAA hyphen 1605.

Techniques: Infection, Saline, Flow Cytometry

Journal: RSC Advances

Article Title: Sterol-like natural products and other secondary metabolites with antimicrobial and antiplasmodial activities from Penicillium tanzanicum

doi: 10.1039/d6ra06849a

Figure Lengend Snippet: Antimicrobial activity (MIC, µg mL −1 ) of crude extract and compounds 1–16 a

Article Snippet: Single colonies obtained from agar plates of Gram-positive bacteria Staphylococcus aureus ATCC 29213, Methicillin-resistant/Vancomycin-intermediate S. aureus (MRSA/VISA) ATCC 700699, Enterococcus faecalis ATCC 29212, and E. faecium ATCC 35667, and Gram-negative bacteria Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853 and Acinetobacter baumannii BAA-747 were grown in Mueller–Hinton Broth (MHB, BD Difco, USA) and the yeast Candida albicans ATCC 24433 in YPD medium (1% yeast extract, 2% peptone, and 2% dextrose).

Techniques: Activity Assay